Postdoc in epigenetics and chromatin dynamics

Description of the workplace

The Epigenetics and Chromatin Dynamics research group at the Department of Experimental Medical Science within the Faculty of Medicine is currently conducting research on the mechanisms underpinning the epigenetic control of the repetitive genome in stem cell models of early human development. The group was established in 2022 by Dr Christopher Douse and currently consists of seven researchers. The group works closely with in close alignment with strategic infrastructures within the Medical Faculty, particularly Lund Stem Cell Center. Our lab is located at BMC in Lund. As a workplace, we ensure a good and safe work environment with respect and consideration for each other. We strive to create conditions for job satisfaction, development, and participation for all employees.

Project description

The project involves the study of the epigenetic control and impact of genomic repeats in human brain development and disease.

Tasks and responsibilities

At Lund University, a postdoctoral position shall provide the opportunity for scientific and pedagogical merit. There is primarily scope for merit in research, but also for some higher education pedagogical training. Teaching may also be included in the duties.

This position primarily consists of research tasks focusing on fundamental, mechanistic questions of transcriptional regulation in experimental molecular and (neural) stem cell biology. You will be responsible to conduct stem cell culture, in vitro neural differentiations and chromatin biochemistry. You will collaborate with the group leader to write research manuscripts related to this work. You will attend local, national and international conferences to communicate findings. You may also be expected to participate in the supervision of undergraduate and master’s students.

Qualifications

Requirements for the position are

• doctoral degree or equivalent foreign degree in biological sciences, molecular biology or a closely related discipline. The doctoral degree must have been obtained no later than the date on which the appointment decision is made.
• ability to develop and conduct high-quality research.
• teaching ability
• you have deep experience stem cell culture and neural differentiation and cell imaging
• you have extensive experience in chromatin biochemistry for example immunoprecipitations and CUT&RUN
• you have expertise and particular interest in mechanisms of epigenetic and transcriptional regulation of gene and transposable element expression in human cell models
• you have experience in functional genomic methods to study epigenetics and transcription such as ChIP and RIP-seq
• you are self-motivated, persistent and collaborative with an analytical mind and capacity to structure more than one project in parallel
• you have the ability to communicate complex findings clearly
• you speak and write English fluently

Merits for the position are

• Applicants who graduated no more than three years before the closing date for applications
• a detail-oriented attitude, good organization skills and team-spirited attitude are meritorious for this position
• an ability to support grant applications and paper writing especially in generating high quality figures is a further merit

The assessment of applicants will primarily be based on their scientific merits and potential as researchers. Particular emphasis will be placed on scientific ability within the subject area.

What we offer

Lund University is a government agency, which means that you get special benefits, generous holidays and a favourable occupational pension.

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About the employment

The position is a fixed-term position for two years, 100% with a start date of 2026-12-01 or as agreed. Employment at Lund University is based in Sweden, so you are expected to be able to perform your work on site in Lund.

The position is limited to a minimum of two years and a maximum of three years, in accordance with the collective agreement on fixed-term employment as a postdoctoral researcher (Arbetsgivarverket). A position as a postdoctoral researcher is intended as an initial step in your career and as an opportunity to further deepen and broaden your research expertise

Other information

Interviews will be conducted on our premises in Lund in the last week of October or first week of November.

How to apply

You apply for the position via the university's recruitment system. The application should include a short (max 1-page) personal letter explaining why you are interested in the position and how the position matches your qualifications. The application should also include your PhD degree certificate, CV and details of references.