Research Fellow in Computational Cancer Biology - Part-time 0.8 FTE

Research Fellow in Computational Cancer Biology to join the Fisher Lab’s ambitious and multidisciplinary research programme focused on understanding cancer using AI to generate digital tumour twins. This programme aims to transform cancer research and precision oncology by developing a new generation of transparent, interpretable and trustworthy artificial intelligence technologies that integrate large-scale biological and clinical data with mechanistic models of cancer. Cancer is a complex, multi-scale disease involving interacting processes across the molecular, cellular, tissue and organ levels. At the same time, advances in genomics, molecular profiling, pathology, imaging and clinical data collection have generated unprecedented volumes of multimodal cancer data. A major challenge is to integrate these diverse data sources into coherent computational frameworks that can generate biological insights, support clinical decision-making and accelerate therapeutic discovery. The Fisher laboratory addresses this challenge through the development of tumour digital twins, which are executable mechanistic models that capture the biological behaviour of individual tumours and can be used to predict disease progression and treatment response. A central goal of the programme is to combine advances in generative AI, computational biology and formal verification to automatically construct transparent, logic-based models directly from large-scale cancer datasets, while ensuring that these models are robust, explainable and mathematically validated. About the role The successful candidate will play a key role in the integration and analysis of multi-omics and clinical cancer datasets, contributing to the development and validation of AI-enabled tumour digital twins. Working at the interface of cancer biology, bioinformatics, machine learning and computational modelling, the postholder will collaborate closely with a multidisciplinary team of biologists, clinicians and computer scientists. The work will contribute to the discovery of novel therapeutic targets, the identification of patient-specific treatment strategies and the development of trustworthy AI technologies for precision cancer medicine. This is an exciting opportunity for a computational biologist or a bioinformatician who is passionate about combining cutting-edge data science with biological discovery and translational impact, and who wishes to contribute to a research programme at the forefront of cancer systems biology and trustworthy AI. Appointment at Grade 7 is dependent upon the successful award of a PhD . Candidates who have not yet been awarded their PhD may be appointed initially at Research Assistant Grade 6B (with progression to Grade 7 and backdated salary adjustment upon submission of the final corrected PhD thesis. For more details about the Fisher Lab, please visit: www.ucl.ac.uk/cancer/fisher-lab This post is funded for 3 years in the first instance, with a probationary period of 9 months. The position is available from 1 st October 2026 , and early availability would be advantageous. Interviews will be held in September 2026. Applications should include a CV and a Cover Letter: In the Cover Letter, please provide evidence of the essential and desirable criteria in the Person Specification part of the Job Description. (By including a Cover Letter, you can leave blank the 'Why you have applied for this role' field in the application form, which is limited in the number of characters it will allow.) About you You will have a PhD, or be nearing completion of a PhD, in Computational Biology, Bioinformatics, Cancer Biology, Systems Biology, Genomics or a related discipline, together with experience analysing large-scale biomedical and multi-omics datasets. You will possess strong programming skills in R, Python and MATLAB, excellent analytical and problem-solving abilities, and experience applying computational approaches to biological research. Experience in cancer biology, computational oncology or bioinformatics is essential, while familiarity with AI and machine learning approaches would be advantageous. You will be an organised, collaborative and proactive researcher, able to work effectively across multidisciplinary teams and communicate complex scientific concepts to a range of audiences. Most importantly, you will be excited by the opportunity to contribute to innovative research at the forefront of computational cancer biology and precision medicine. What we offer As well as the exciting opportunities this role presents we also offer some great benefits some of which are below 41 Days holiday (including 27 days annual leave 8 bank holiday and 6 closure days) Defined benefit career average revalued earnings pension scheme (CARE) Cycle to work scheme and season ticket loan On-Site nursery On-site gym Enhanced maternity, paternity and adoption pay Employee assistance programme Staff Support Service Discounted medical insurance For rewards and benefits at UCL please visit: Staff Benefits | UCL People & C ulture - UCL – University College London Our commitment to Equality, Diversity and Inclusion As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here: Equality, Diversity & Inclusion: Think differently, do differently. | Office of the President and Provost (Equality, Diversity & Inclusion) - UCL – University College London