Research Associate in Translational Proteomics of Cartilage

Job Description

The Rice Lab within the Division of Musculoskeletal and Dermatological Sciences wish to appoint a laboratory-based Research Associate with mass spectrometry-based proteomics experience to an exciting project exploring the effect of collagen glycosylation on cartilage health in the context of osteoarthritis. We seek a highly motivated postdoctoral mass spectrometrist/proteomics expert with cell biology experience. During this position, the post-holder will undertake a range of molecular and cell biological activities, including use of CRISPR-Cas9, primary cell culture, and western blotting, followed by downstream LC-MS/MS to characterise the chondrocyte and extracellular matrix proteome. The successful candidate would be expected to perform experiments independently and to work alongside the Principal Investigator to conceptualise studies, design experiments and publish their findings in appropriate journals. The role will involve contributing to a team-science approach in the laboratory, supporting other team members and trainees intellectually and practically and working collaboratively with internal and external collaborators. This will be a highly collaborative project with the proteomics laboratory of Professor Matthias Trost at the University of Manchester. The successful candidate would be expected to be curious and rigorous, with demonstrable knowledge of cell biology relevant to the research focus of the laboratory and substantial hands-on experience with mass spectrometry platforms. What you will get in return: · Fantastic market leading Pension scheme · Excellent employee health and wellbeing services including an Employee Assistance Programme · Exceptional starting annual leave entitlement, plus bank holidays · Additional paid closure over the Christmas period · Local and national discounts at a range of major retailers As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit. Our University is positive about flexible working. Hybrid working arrangements may be considered. Please be aware that due to the number of applications we are unfortunately not able to provide individual feedback on your application. Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies. Any recruitment enquiries from recruitment agencies should be directed to recruitmentservices.people@manchester.ac.uk Any CV’s submitted by a recruitment agency will be considered a gift. Enquiries about the vacancy, shortlisting and interviews:

Name: Dr Sarah Rice

Email: sarah.rice@manchester.ac.uk

General enquiries

Email: recruitmentservices.people@manchester.ac.uk

Technical support

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Interviews will take place on the 23rd and 24th of February. This vacancy will close for applications at midnight on the closing date.

Please see the link below for the Further Particulars document which contains the person specification criteria.